The PREPARE trial is a randomized control trial aimed at improving surgical outcomes for older patients with frailty through prehabilitation. This discussion covers the inspiration behind the trial, the structure of the prehabilitation program, and the trial’s results. Despite not finding significant improvements in the primary outcomes across all patients, the trial revealed that those who adhered to the program showed clinically meaningful improvements.

The conversation delves into the challenges of patient adherence, the role of technology, and the importance of personalized interventions in prehabilitation.

Presented by Mike Grocott and Kate Leslie on location at the International Anesthesia Research Society (IARS) and Society of Critical Care Anesthesiologists meeting in Honolulu, Hawaii, with their guest, Daniel McIsaac, Associate Professor of Anesthesiology & Pain Medicine, University of Ottawa, Canada.

Further resources:

We mention Chelsia Gillis, Assistant Professor in the School of Human Nutrition in the Faculty of Agricultural and Environmental Sciences at McGill University. She has appeared on this podcast multiple times, this presentation is a good place to start: TopMedTalk: Nutritional screening and assessment tools for prehab | World Congress of Prehabilitation

We also discuss The Duke Activity Status Index (DASI) can be found here: https://www.mdcalc.com/duke-activity-status-index-dasi

There’s also an excellent presentation on which relates to this conversation here: TopMedTalk: EBPOM London 2020 | Functional Assesment

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